SEPARASE LOSS OF FUNCTION COOPERATES WITH THE LOSS OF P53 IN THE INITIATION AND PROGRESSION OF T- AND B-CELL LYMPHOMA, LEUKEMIA AND ANEUPLOIDY IN MICE.

Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice.

Cohesin protease Separase plays a key role in faithful segregation of sister chromatids Gardening Tools by cleaving the cohesin complex at the metaphase to anaphase transition.Homozygous deletion of ESPL1 gene that encodes Separase protein results in embryonic lethality in mice and Separase overexpression lead to aneuploidy and tumorigenesis.Howeve

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Consumer engagement in health care policy, research and services: A systematic review and meta-analysis of methods and effects.

To assess the effects of consumer engagement in health care policy, research and services.We updated a review published in 2006 and 2009 and revised the previous search strategies for key databases (The Cochrane Central Register of Controlled Trials; MEDLINE; EMBASE; PsycINFO; Fridge Door Stopper CINAHL; Web of Science) up to February 2020.Selectio

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